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Which celebrities take Ozempic – and who denied it? 13 stars who spoke out about weight-loss drugs, from Tesla CEO Elon Musk and Khloé Kardashian, to Amy Schumer and Real Housewives cast members

Celebrities like Elon Musk, Amy Schumer, Khloé Kardashian, Julia Fox and Margaret Josephs all have something to say about weight loss drug Ozempic. Photos: AP; Reuters; @laquan_smith, @juliafox, @therealmargaretjosephs/Instagram
Celebrities like Elon Musk, Amy Schumer, Khloé Kardashian, Julia Fox and Margaret Josephs all have something to say about weight loss drug Ozempic. Photos: AP; Reuters; @laquan_smith, @juliafox, @therealmargaretjosephs/Instagram

  • FDA-approved Ozempic and Wegovy are both semaglutides while tirzepatide, marketed as Mounjaro, is being used off-label – NBA star Charles Barkley credits the latter for losing over 28kg in six months
  • Tesla CEO Elon Musk, Rosie O’Donnell, Amy Schumer and RHONJ star Dolores Catania admit that they had used the anti-diabetic medication, but Khloé Kardashian says she just worked out to lose weight

If Ozempic wasn’t mainstream before, it definitely is now – Jimmy Kimmel joking about A-listers using the drug during the 2023 Oscars proved as much.

Elon Musk and Amy Schumer have admitted to taking the weight-loss drug while other celebrities, such as Khloé Kardashian and RHOBH star Kyle Richards, have denied it.

Boxes of Ozempic, a semaglutide injection drug used for treating type 2 diabetes made by Novo Nordisk, are seen at Rock Canyon Pharmacy in Provo, Utah, US, on March 29. Photo: Reuters
Boxes of Ozempic, a semaglutide injection drug used for treating type 2 diabetes made by Novo Nordisk, are seen at Rock Canyon Pharmacy in Provo, Utah, US, on March 29. Photo: Reuters
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Ozempic has become the byword for semaglutide and similar drugs that cause weight loss, regardless of which brand a person is taking or why, and there have even been shortages of the drugs as people clamour to get their hands on them.

Anti-diabetic medication Ozempic made by Danish pharmaceutical company Novo Nordisk. Photo: TNS
Anti-diabetic medication Ozempic made by Danish pharmaceutical company Novo Nordisk. Photo: TNS

Ozempic and Wegovy are both forms of semaglutide, a drug originally developed for diabetes. They are brand names used by the drug manufacturer, Novo Nordisk. Semaglutide was FDA-approved to treat obesity in 2021. Tirzepatide, marketed as Mounjaro, is a similar “game-changer” drug. It is yet to be approved for weight loss, but can be used off-label for this purpose.

A man preparing an Ozempic injection, which controls blood sugar levels. Photo: Shutterstock
A man preparing an Ozempic injection, which controls blood sugar levels. Photo: Shutterstock

They work by suppressing appetite, but side effects such as muscle loss, nausea and diarrhoea have been reported – and it’s common to regain the weight after stopping treatment.

So which celebrities have been associated with the drug, and what do they have to say about it?

1. Amy Schumer

Comedian Amy Schumer at the 2016 Met Gala. Photo: @ohmypnd/Twitter
Comedian Amy Schumer at the 2016 Met Gala. Photo: @ohmypnd/Twitter